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Tesamorelin

Also known as Egrifta, TH9507

Tesamorelin is an FDA-approved GHRH analog specifically studied and approved for reducing visceral abdominal fat. It's more stable than native GHRH and produces robust GH/IGF-1 increases with particularly strong effects on belly fat reduction.

Typical dosing
1000–2000 mcg · Once daily
Administration
SubQ
Half-life
~26–38 minutes
Level
intermediate

How it works

Stabilized GHRH analog that binds GHRH receptors with high affinity, stimulating GH release and downstream IGF-1 production. Superior stability vs sermorelin due to trans-3-hexenoic acid modification.

Benefits

  • FDA-approved for visceral fat reduction
  • Strong reduction in abdominal/visceral fat
  • Significant GH and IGF-1 elevation
  • Improved lipid profiles
  • Cognitive benefits (studied for MCI/Alzheimer's prevention)
  • Body composition improvements

Dosing

1000–2000 mcg · Once daily

FDA-approved dose is 2mg daily. Research/biohacker protocols often use 1–2mg daily.

Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.

Reconstitution

2mg vial with 2mL BAC water = 1mg/mL

Helix’s free reconstitution calculator gives you the exact draw volume → get the app

Common stacks

Reported side effects

  • Injection site reactions
  • Water retention
  • Joint pain
  • Carpal tunnel
  • Glucose intolerance possible

Who it’s for

Those focused on visceral fat reduction, metabolic health, or wanting a research-backed GHRH analog with FDA approval data. Intermediate users.

Track Tesamorelin in Helix

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