Selank & Semax Blend

How it works

Selank modulates GABA-A receptors (like benzodiazepines but non-addictive) and regulates IL-6/enkephalin expression for anxiolysis. Semax stimulates BDNF and NGF production, activates dopaminergic and serotonergic systems, and provides neuroprotection via ACTH(4-7) fragment activity.

Benefits

• Anxiety reduction + cognitive enhancement synergy
• Selank provides anxiolytic/anti-anxiety effects
• Semax drives BDNF elevation and neuroplasticity
• Improved focus and mental clarity
• Mood stabilization
• Neuroprotective from both components
• Well-tolerated daily use profile

Dosing

250–500 mcg · Once to twice daily

Typically administered as nasal spray. 250–500mcg per component per dose. Can use SubQ. Best taken in morning or afternoon — Semax can be stimulating.

Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.

Reconstitution

10mg total blend in 2mL = 5mg/mL per component. For nasal use: dilute further to 250–500mcg per pump in preserved saline.

Helix’s free reconstitution calculator gives you the exact draw volume → get the app

Common stacks

Reported side effects

• Generally very well tolerated
• Mild nasal irritation (nasal route)
• Headache (rare)
• Increased anxiety in sensitive individuals (Semax — start low)

Who it’s for

Those dealing with anxiety and cognitive performance simultaneously. Students, professionals, or biohackers seeking a daily calm-focus nootropic. Beginner-friendly and well-studied.