Tamoxifen (Nolvadex)
Also known as Nolvadex, Tamoxifen Citrate
A SERM that is FDA-approved for breast cancer and widely used in performance circles to prevent or treat gynecomastia and to restore natural testosterone in post-cycle therapy.
How it works
Antagonizes estrogen receptors in breast tissue and the hypothalamus (while acting as an agonist in bone and liver), increasing gonadotropins.
Benefits
- Blocks estrogen at breast tissue (prevents/reverses gyno)
- Raises LH/FSH and testosterone in PCT
- Oral
Dosing
10–20 mg · Daily (oral)
Gyno/PCT use is typically 10-20 mg/day; higher acute doses are sometimes used for active gyno.
Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.
Common stacks
Reported side effects
- Hot flashes
- Mood changes
- Nausea
- Reduced IGF-1
- Rare clotting risk
Who it’s for
Those managing estrogenic side effects or running PCT, ideally with clinic guidance.
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