Gonadorelin
Also known as GnRH, Gonadotropin-Releasing Hormone, Factrel
Synthetic gonadotropin-releasing hormone (GnRH) that prompts the pituitary to release LH and FSH, stimulating the body's own testosterone and sperm production. A shorter-acting, more physiologic alternative to HCG that TRT clinics increasingly favor.
How it works
Binds pituitary GnRH receptors, triggering LH and FSH secretion, which in turn stimulate testicular Leydig and Sertoli cells.
Benefits
- Maintains natural testosterone and testicular function on TRT
- Supports fertility
- More physiologic (pulsatile) stimulation than HCG
- Short half-life clears quickly
Dosing
100–200 mcg · 2-3x per week or more
Typical TRT-adjunct dosing is 100-200 mcg SubQ 2-3x/week. Its very short half-life means frequent dosing for sustained effect.
Ranges reflect commonly cited research protocols, not a prescription. Dose with a licensed provider.
Reconstitution
Lyophilized; reconstitute with BAC water and refrigerate.
Helix’s free reconstitution calculator gives you the exact draw volume → get the app
Common stacks
Reported side effects
- Injection-site reactions
- Headache
- Flushing
- Nausea
- Mild hormonal fluctuations
Who it’s for
Men on TRT preserving fertility and testicular function. Clinic-supervised.
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